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Associate Principal Scientist, Cellular Pharmacology and Lead Discovery
Location:
Abee
Description:
Job Description Our Research Laboratories (MRL) in South San Francisco is seeking an Associate Principal Scientist with strong expertise in complex cellular model/assay development, mechanistic receptor pharmacology, and lead discovery to join our Quantitative Biosciences (Pharmacology) department. The successful candidate will be responsible for the design, execution, and interpretation of mid/high throughput in vitro/ex vivo assays and mechanistic experimentation to advance early drug discovery projects from target concept through lead optimization. The candidate will work closely with a team of multidisciplinary quantitative scientists and other stakeholders to define strategies for screening, assays/models, and key mechanistic studies to advance a diverse portfolio of small molecule and biologic preclinical candidates targeting cardiovascular and metabolic disorders. In addition, the Associate Principal Scientist will participate in business development diligence efforts and establish internal/external relationships that drive portfolio progression. We value transparent communication, creative-thinking, teamwork, and rigorous scientific exploration. If you are a highly motivated candidate and team player with a strong desire to impact cardiometabolic drug discovery, we invite you to consider joining our team. Key job duties: Drive hit/lead discovery and optimization plans in collaboration with therapeutic area stakeholders, Chemistry, Biologics, and multidisciplinary Quantitative Bioscience teams Develop and implement potency, selectivity, and mechanistic assays to characterize diverse targets, pathways, and areas of biology, using a wide range of experimental methods Design and execute complex assays utilizing diverse cell models and advanced technologies in support of target validation through lead optimization Represent Quantitative Biosciences department in multi-disciplinary drug discovery project teams to set pharmacological strategies. Visit ListedBuy for more information.
Company:
Merck & Company
Posted:
December 22 2023 on ListedBuy
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More About this Listing: Associate Principal Scientist, Cellular Pharmacology and Lead Discovery
Associate Principal Scientist, Cellular Pharmacology and Lead Discovery is a Science & Pharmaceutical Scientist Job at Merck & Company located in United States. Find other listings like Associate Principal Scientist, Cellular Pharmacology and Lead Discovery by searching Oodle for Science & Pharmaceutical Scientist Jobs.
Associate Principal Scientist, Cellular Pharmacology and Lead Discovery is a Science & Pharmaceutical Scientist Job at Merck & Company located in United States. Find other listings like Associate Principal Scientist, Cellular Pharmacology and Lead Discovery by searching Oodle for Science & Pharmaceutical Scientist Jobs.